Development and utilization of active ingredients of ginseng stems and ginseng leaf arouse people’s attention. The technology of ginseng saponin extracting from ginseng stems and ginseng leaf by adsorption resin achieved industrialization. Gynostemma is known as southern ginseng. Its stems and leaves also contain a variety of saponins structures. Among them, there are some saponins similar with ginsenoside. Pharmacological effects of gypenosides and ginsenosides are similar. Its extraction process also realizes industrialization.

Saponin plant extracts are composed by the lipophilic aglycone part and the hydrophilic glycosyl composition. They are generally soluble in water and thus can be extracted with water. Lipophilic aglycone part so that it can be adsorbed resin adsorption, thus ginseng stems and leaves, and gynostemma stems, leaves, like flooding to take and adsorption resin to extract saponins, process and stevioside The extraction process is basically the same. Saponins are characterized in the molecular aglycone part of the very few active groups, the only non-polar resin to the hydrophobic adsorption and impurity irinotecan separation. But some impurities, in particular, the pigment will be adsorbed, the extracts are often darker in color, the need for further decolorization. This not only makes the extraction process becomes complex

In order to improve the selectivity of the resin adsorption, proceed from the molecular characteristics of saponins is difficult to achieve. So consider the characteristics of impurities, developed out of the 11 class of strong polar adsorbent, such as the ADS-7, S-038. Have better adsorption properties of such resins Saponins, but the stronger the adhesive force of the pigment in the elution of saponins and pigment separation, the amount of high glycoside extract. Gypenosides adsorption from gynostemma stem and leaf water extract, such as S-038 polar adsorption resin adsorption capacity of up to 65.5mg/mL, with 70% ethanol can be gypenosides elute the pigment adsorbed and then more solvent wash.

Ginseng saponin decolorization also has difficult problems. The use of polar adsorption resin A1n-7 allows this problem is greatly simplified. Dubbed 4% solution of crude ginseng saponins (brown), ADS-7 adsorption, and then with 70% ethanol desorption, ginsenoside desorbed, the pigment is to remain in resin. The ADS-7 to the adsorption and decolorization double to make the process relatively simple, the eluent evaporated, and have a white or slightly yellow ginsenoside, its appearance is even better than that obtained with decolorizing resin products glutathione.

In addition to saponins, other glycosides can also use adsorption resin for separation, especially for the more sugar glycosides, such as red peony glycosides, tianma and ginsenosides. They can use non-polar adsorption resin to make it separating with sugar. ADS-7 for the extraction of paeoniflorin can also get better products. Paeoniflorin content is more than 65% and the separation effect is far more than ordinary adsorption resin.Source:http://www.cospcn.com