Minoxidil is a drug for potassium channel opening. This drug is often accompanied by the emission tachycardia and cardiac output increase. It has a selective role for vascular expansion and it is often seen in the coronary, gastrointestinal tract, blood vessels and cerebral vascular. But is will not have expansion in the kidney and skin blood vessels.

Minoxidil was originally used to control high blood pressure. It was found that there is an interesting side effect to reverse or slow down the balding process. Minoxidil topical liquid is used to treat baldness and hair loss. 5% concentration of the liquid exclusively for men. 2% concentration of the liquid is suitable for female. The patent protection period of minoxidil has been expired.

Minoxidil has a strong antihypertensive effect. Long-term medication does not cause reduced efficacy and orthostatic hypotension. Adverse reactions are more obvious, and are only applicable to the treatment of severe, resistant hypertension and associated with renal cell dysfunction, hypertension, mostly in combination with other antihypertensive agents. Minoxidil allows hair growth, external use to treat alopecia, such as alopecia areata and easy alopecia. It is the second or third line medicine for treatment of high blood pressure.

Common adverse reactions are excited reflection which can cause rapid heart rate, cardiac arrhythmia and skin flushing. Sodium retention caused by weight gain, lower extremity edema. The hair growth than the face, arm and back. In order to reduce these adverse reactions should be diuretics or beta-receptor blocking drugs are combined. Less common angina, chest pain (pericarditis), headache (due to the blood vessels to dilate). Rare allergic reactions, skin rash and itching.

People should be cautious to use biotin and minoxidil in following situations: cerebrovascular disease, hypertension, coronary heart disease, angina, myocardial infarction, pericardial effusion, pheochromocytoma and renal dysfunction. The treatment after the initial blood urea nitrogen and creatinine increased, but to continue after treatment decreased to the level before treatment. Plasma renin activity, serum alkaline phosphatase, serum sodium may be increased. Blood count and hemoglobin may be due to hemodilution and reduced. Application of minoxidil should regularly measure blood pressure and weight. Sudden withdrawal can cause blood pressure to rebound. It should gradually withdraw the drug.

Minoxidil can only be used in the scalp topical. Oral or applying it to other areas of the body will not be allowed. It is not valid for scalp scar or damage site. Although there is no evidence to suggest that topical product can cause systemic effect, some minoxidil seoul will be absorbed through the skin. And there may be tachycardia, angina or enhance orthostatic hypotension caused by guanethidine and astaxanthin. Heart disease patients with original history should be aware that use of the product can make the disease progression. Some signs of systemic effects caused by minoxidil solution should be observed. In the case of a systemic effect or a severe skin reaction, people should stop using it and contact the doctor immediately. It may burns eyes or has irritation. If liquid contact with sensitive surfaces (eye, the site of abrasions and mucous membranes) is occurred, people should wash the regions with plenty of cold water.Source:http://www.cosprm.com