One of the most common malignant tumors is liver cancer in China. Its deaths rate ranks first three among malignant tumors of the digestive system. It is just after stomach cancer and esophageal cancer and all of them have serious impact on public health and life. To find the anti tumor active ingredient from plants is an important area of ​​cancer research. Xinjiang is the kingdom of Chinese wild plant extracts. The special light, heat resources and a strong temperature difference between day and night breed biomes which have special anti-mutagenic pharmacological effects. Study focus on Xinjiang plant multiflora rose, black currant, olester, and almond extract. They inhibit human hepatoma cell‘s growth. It is designed to accumulate data for the further development of anticancer drugs.

Using low dose of multiflora rose, blackcurrant can prevent cell growth and proliferation of tumor cell. The density is less than the negative control group, the dispersed cells in the volume decreases, lack of dimensional consideration of individual cells are combined damaged. The dose range of high and low doses. Different concentrations of substances in human hepatocellular carcinoma tumor cell-7704 Qcy prohibition Multiflora rose, blackcurrant, olester and almond extract prevented by increasing the dose and confirmed Multiflora inhibitory effect resulting from a lack of long-lasting and improved antitumor effects and oleaster almonds and time dependence.

 

Tumor in the first murder in human health, the development of antitumor components factory at one focus of cancer. Xinjiang, a vast territory and rich resources Multiflora rose, black currant, L., spread almonds in Xinjiang. Various concentrations of wild rose, blackberry, LG, almond extract objects from the human hepatoma cell THI-analysis to assess the value and the observed changes in cell morphology, the initial selection of anticancer drugs.

High dose of pharmaceutical raw materials multiflora rose, black currant, almond extract and molester significantly inhibited diffuse lines of human hepatoma cells Qcy-7404. These results enhance immunity, anti-mutagenic, anti-tumor effect is consistent with Multiflora rose, blackcurrant, L., almonds. In particular, Multiflora rose and currant group of human hepatocellular carcinoma tumor cells damaged and wrinkled, fuzzy boundaries, poor lighting, lack of three-dimensional sense, while some cellular areas, the majority of cells, condensation phenomena, such as morphological changes in small portions major role is clear that again, this will lead to further evidence THI analysis. Closed is essential for cell growth and fan also a cell surface glycoprotein normally secreted by cells, motility, in particular, the carrier binding plays an important role in the growth and changes the nature of the water layer of cells, preventing the binding of cells to support the financial unit.

 

MIT is widely used to determine the sensitivity of tumors in vitro. Mitochondria dehydrogenase in normal activity living cell can reduce MTT to purple. And there is a linear relationship between the OD value of the generated and the number of cell survival. The test substance group of tumor cell is limited. OD values ​​are significantly lower than the negative control group. Multiflora rose, black currant, elaeagnus angustifolia, and almond extract may interfere with cell metabolism and change nature of the cell coat to inhibit tumor cell proliferation. Action mechanism and active ingredients of multiflora rose, black currant, elaeagnus angustifolia and almond extract in inhibiting human hepatoma cell line need to be further studied.Source:http://www.cospcn.com