Loss of glutathione is a major factor causing liver disease. In the plasma and liver of viral hepatitis, alcoholic or non alcoholic hepatitis patients, the level of glutathione is significantly reduced. The research results on obstructive pulmonary disease and pulmonary fibrosis including lung disease show the lack of glutathione levels.

NAC can achieve the desired level of glutathione in body tissues. So the supplement NAC products are becoming increasingly common. But experts reclaim that people should not eat too much. There is evidence that supplementation of high doses of NAC may produce oxidants like effect and increase the body's oxidative stress.

Other studies have confirmed that multiple sclerosis patients the ability to remove free radicals toxicity reduced, mainly due to reduced glutathione peroxidase activity. The results of these studies also found that selenium supplementation resveratrol can significantly increase the activity of glutathione peroxidase. Study of HIV-infected patients showed that selenium supplementation to HIV positive in vivo activity of glutathione peroxidase enhancement. This may be due to the Selenium induced glutathione peroxidase activity of the reasons. In the glutathione level of loss, the lower the activity of glutathione peroxidase and atherosclerosis occur between there was a correlation.

Loss of glutathione standards can greatly inhibit the function of the immune system, and make the body vulnerable to infection. Similarly, chronic viral infections can also loss of glutathione storage. The study found that those who have been diagnosed with hepatitis C and early HIV infection in the blood, low glutathione standards.

The loss of glutathione levels are also related with some nervous system diseases. Because the brain, a high degree of oxygenated and rich in polyunsaturated lipids, the brain become active place cells attack the body from free radicals generated due to nutrient deficiencies. Parkinson's disease patients on lipid correlation between the oxidation levels and glutathione levels, showing that the loss of glutathione as a causative factor. Patients with Alzheimer's glutathione levels is not normal is low.

Despite intestinal absorption of dietary glutathione, the nutritional supplement of glutathione is not so simple. Although oral administration containing glutathione supplements can increase the glutathione level, there are significant differences between different individuals. Research reports refer that oral glutathione-containing supplements can make glutathione levels increased by 2-5 times. The results of another study have shown that the absorption of a dosage of 3,000 mg glutathione is negligible. This absorption level’s uncertainty will cause people worried about the tonic effect from added glutathione. Glutathione is a tripeptide (protein fragments), so it may be hydrolyzed in the digestive process. This is why some experts believe that with some other feasible method compared, oral glutathione-containing supplements in the economy is uneconomical.Source:http://www.cospcn.com