The spices belong to high value-added fine chemical products. It is mainly used in food, household chemicals, smoke, flavored, wine, cosmetics and pharmaceutical industry. In addition to individual situations, spices can not be directly used for consumer goods. After becoming flavors, they can be used in food and cosmetics. The flavor is deployed with a variety of spices (sometimes with a certain amount of solvent and other additives).It is a mixture with certain flavors.

According to the sources of spices, it can be divided into two major categories: natural flavors and synthetic fragrances. Natural spices can be divided into animal natural spices and vegetable natural spices categories, namely, directly from the plants and animals in the Synthetic fragrances using natural raw materials or chemical raw materials, preparation of the spice compounds by chemical synthesis methods.

The fragrance industry is less investment, fast convergence, accumulation, swap industry. In the past 20 years, International Flavors & Fragrances trade sales were growing trend. Flavor API supplier in the world of fine chemical industry, second only to the pharmaceutical industry, ranking second. Flavor industry and people living standards improve, the development of the food industry are closely related. From a global perspective, in recent years, the growth rate of the Flavor Industry has been higher than the average growth rate of other industries. The fastest growing regions in Asia-Pacific region, due to the current low per capita consumption of the next decade will be the needs of the most productive country in the world. Flavor industry wide market and a large amount of industry in China are described as a sunrise industry. China has unique resources of natural spices, is the world's largest natural spice-producing countries, has the advantage of low raw material costs, and therefore has much room for development and market potential.

With the human awareness of environmental protection and for their own health concerns, natural spices and the flavor of the deployment of natural spices will become a mainstream consumer, producers and businessmen should be noted that trend. Natural level spice is very popular in Europe and the United States market, its price is much higher than ordinary synthetic fragrances, synthetic fragrances, or even several times more than 10 times. Growing market demand of natural spices, so the use of biotechnology to the production of natural spices becomes increasingly important for people. Which microbiological method is the production of safer, aroma compounds and their complexes of high biological activity of the most promising approaches.

Biotechnology in today's rapid development and transformed into the era of the goods, bio-chemical industry developed very rapidly, according to official projections, the future will have 20% to 30% of the chemical process will be replaced by biotechnology processes. With the dwindling non-renewable resources such as oil, the world's population and environmental pressures increase, application of modern bio-technological innovation and the trend to replace the traditional chemical process more and more attention has been paid, as traditional or conventional biotin techniques can not be solved The major issues to bring a new dawn. Strong technical and economic support for the development of biotechnology for the biological production of spices. With the development of biotechnology and the biological production of spices to further improve the technology, there will be more and more spices to the biological production. The application of biotechnology in spices in the early focused on screening microbial strains that can produce aromatic compounds, modern microbial techniques (including genetic engineering) are increasingly being used in enhancing the catalytic efficiency of biocatalysts. We can anticipate that genetic engineering and protein engineering will become the main direction of research and development of spices. The progress of genetic engineering, not only can make the protein (enzyme) was highly expressed, so that the biocatalyst production costs substantially reduced, and change the metabolism of the biocatalyst to be a significant improvement in performance biocatalysts.

Natural spices with biotechnology production need a lot of work crafts: high-yield strains, fermentation conditions optimization, the construction and expression of the genetically engineered bacteria and reduction of the biological cost.

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