Minoxidil is a well-known name to many hair losers. Minoxidil is a vasodilator, and it can be used in high blood pressure. But the system for treatment of hair loss is primarily on dilate blood vessels. Minoxidil is an oral drug for clinical blood pressure.

Minoxidil direct relaxation of vascular smooth muscle, there is a strong role in the growth of small arteries and to reduce peripheral resistance, vasodilatory, blood pressure had no effect on the substrate may contribute to the capacitance venous return. At the same time, may as a reflex control and a positive effect on the frequency, cardiac output and heart rate increase, but does not give rise to orthostatic hypotension. At this time, minoxidil is the clinical two, three lines of a hypotensive agent can be used to treat refractory hypertension and renal hypertension.

Minoxidil is a drug, and of course there are side effects. The most common side effects of oral minoxidil: reflex sympathetic excitation causes palpitations and rhythm disturbances, hirsutism. The most common side effects of irritating topical formulations, dermatitis on medication, redness, itching and other reactions. Although the absorption of topical formulations are very small, but does not rule out the effects of heart disease patients with a disease. Suffering from cerebrovascular disease, hypertension and heart failure factors, heart disease, angina pectoris, myocardial infarction, pericardial effusion, renal failure and other diseases, must be allergic to minoxidil people and patients with pheochromocytoma are blocked.

Hair follicles in vitro addition of minoxidil can be added to a growing culture of hair follicles. Hepatocytes growth factor and follicle stimulating vascular endothelial cell receptors in the dermal papilla are two important growth factor, an important role in the regulation of hair growth. This study shows that minoxidil can stimulate and direct the differentiation of epithelial cells and hair follicle to promote angiogenesis, increase local blood circulation.

At present, there is sufficient clinical studies have confirmed that minoxidil has androgenic alopecia, alopecia areata is a good effect, but a lengthy drug maintains their effectiveness. The shorter the hair, the smallest area, a better prognosis. High levels of efficiency at low concentrations of large clinical trials have confirmed that the current minoxidil hair care is safe.

The main adverse effects of minoxidil solution are hirsutism. In clinical practice to use minoxidil, cosmetic raw material suppliers found that patients who spend more time with minoxidil get varying degrees of hirsutism. In addition, minoxidil may cause irritation, and allergic reactions, symptoms itching and scaling of the scalp. But the tests on patients show that they are caused by allergic contact dermatitis patch .Propylene glycol as a solvent, it is true of allergens. The replacement of solvent will prevent the allergic reaction. It is worth mentioning that the minoxidil was approved to have indications of androgenic alopecia (also known as male pattern baldness), and alopecia areata. The consumer should consult a dermatologist before you buy any of them. You need to inquire your doctor or pharmacist before using it. Source:http://www.cosprm.com